Dr. Devin Schweppe is an Assistant Professor in the Department of Genome Sciences at the University of Washington. His research is focused on developing, improving, and generating diverse and representative datasets and databases to thoroughly understand the complex biological landscape of cancer cells with and without clinical interventions. His research program aims to elucidate the many factors that lead to different responses to small-molecule therapies in lung cancer. Multiplexed proteomics will be used to quantify thousands of human proteins from diverse cellular backgrounds in response to clinical therapeutics, mapping the dynamic proteome response. The protein-centric map of the cell states, due to environmental, genetic, and clinical factors, will then be used to investigate how they relate to different clinical outcomes.

Dr. Schweppe’s studies have a strong potential to identify how cell state dynamics regulate the cellular response of tumors to cancer therapeutics. His approach is anticipated to significantly advance the field towards personalized medicine and treatment.