Currently, there is a lack of a cost-effective, scalable, and robust clinical assay to map this interaction of the SARS-CoV-2 RNA, protein components, and human tissues. The research team will be creating a simple, inexpensive method for the multiplexed imaging of both the host and SARS-CoV-2 RNA and protein in human tissue samples. This direct visualization of the SARS-CoV-2 virus within the native tissue context will be essential to understanding the pathology of COVID-19 infection and inform cancer providers and surgeons of how COVID-19 interacts with cancer cells and the altered immune environment of the tumor.